Synlett Article Online via eFirst

Our latest publication has appeared online as an eFirst article in Synlett. The ‘SYNPACTS’ highlights recent advances in using organocatalysts to control regioselectivity and stereoselectivity in glycosylation reactions. As well as our own work in the area, it discusses work by the groups of Taylor, Schmidt, Jacobsen, and Fairbanks. It was already in press when the latest publication from the Schmidt group on organocatalytic glycosylations appeared online last week in Angew Chem Int Ed DOI: 10.1002/anie.201302158. The Synlett article is the latest from an ongoing collaboration with the Galan group in Bristol (the authors are pictured below: Carmen, Ed & Eoghan).

author photoThe article will be part of a special Synlett print issue celebrating the recent EUCheMs Young Investigator’s Workshop held in Marseille prior to ESOC2013. It can currently be read online as an eFirst article (with a subscription):

Synlett, 2013, eFirst doi: 10.1055/s-0033-1338970


PhD position Available

Thanks to some very recent funding success we now have an opening for a PhD position. EU student fees are included in addition to a stipend. The project will build on recent successes in the area of organocatalytic glycosylations. See our vacancies page for more details. Applications are welcome from students with, or expecting to gain, a first or upper second class honours degree (or equivalent). Candidates should be willing to teach undergraduates. Interested applicants should send a CV and cover letter to Eoghan by email.


Our latest paper goes online in JACS

Our latest paper appeared online yesterday in the Journal of the American Chemical Society. The article describes the results of a detailed study of sulfur ylide epoxidations and aziridinations using a cheap and readily available chiral sulfide (isothiocineole). The sulfide can be made in one step from sulfur and limonene, and is commercially available as either enantiomer (e.g., Aldrich cat 766429; TCI T2578 and T2579). Enantiopure epoxides and aziridines can be easily made using this method which has already been applied in the synthesis of biologically active molecules following our 2010 communication (e.g., OL2011, ACIE 2011) This work is part of a long-standing collaboration with Prof Varinder Aggarwal at University of Bristol, and is a real team effort – well done everybody!

Graphical Abstract ja-2013-05073w_0001The paper can be read online here:

J Am Chem Soc, 2013, asap article. DOI: 10.1021/ja405073w

Open Access: If you do not have a J Am Chem Soc subscription please email Eoghan for a free access code for this article via ACS Articles on Request.


We thank EPSRC, the University of Bristol, Departament d’Educacio I Universitats de la Generalitat de Catalunya, Science Foundation Ireland and Marie-Curie COFUND for support.

J Am Chem Soc is the most cited journal in chemistry and the flagship journal of the American Chemical Society.