Selected Publications

Chem Commun 2023, 59, advance article. M B Reddy, E M McGarrigle*

Chem Sci 2021, 12, 10070-10075. Stereoselective β-mannosylations and β-rhamnosylations from glycosyl hemiacetals mediated by lithium iodide. DOI: 10.1039/D1SC01300A

Org Lett 2020, 22, 8451-8457. V K Duong, A M Horan, E M McGarrigle* Synthesis of Pyridylsulfonium Salts and Their Application in the Formation of Functionalized Bipyridines. DOI: 10.1021/acs.orglett.0c03048

Chem Sci 2019, 10, 508-514. G A BradshawA C ColganN P AllenI PongenerM B BolandY Ortin and E M McGarrigle* — Stereoselective organocatalyzed glycosylations – thiouracil, thioureas and monothiophthalimide act as Brønsted acid catalysts at low loadings. DOI: 10.1039/C8SC02788A

J Org Chem 2016, 81, 11394-11396. A C Colgan, H Müller-Bunz, E M McGarrigle* — Benzylation Reactions in DMF Lead to an Impurity Which Acts as an Organocatalyst Poison in Thiourea-Catalyzed Glycosylations. DOI: 10.1021/acs.joc.6b01914

Org Lett 2015, 17, 5044–5047. J V Matlock, T D Svejstrup, P Songara, S Overington, E M McGarrigle,* V K Aggarwal* — Synthesis of 6- and 7-Membered N-Heterocycles Using α-Phenylvinylsulfonium Salts. DOI: 10.1021/acs.orglett.5b02516 [1 of the top 10 most read articles published in Org Lett in Oct 2015. Highlighted in Synfacts 2015, 11, 1249 V Snieckus, M E Dalziel, and featured in the chemistry views website, 6th October 2015]

Angew Chem Int Ed 2014, 53, 8190-8194. E I Balmond, D Benito-Alifonso, D M Coe, R W Alder, E M McGarrigle,* M C Galan* — A 3,4-trans-Fused Cyclic Protecting Group Facilitates α-Selective Catalytic Synthesis of 2-Deoxyglycosides. DOI: 10.1002/anie.201403543

J Am Chem Soc 2013, 135, 11951–11966. I Illa, M Namutebi, C Saha, M Ostovar, C C Chen, M F Haddow, S Nocquet-Thibault, M Lusi, E M McGarrigle,* V K Aggarwal* — Practical and Highly Selective Sulfur Ylide-Mediated Asymmetric Epoxidations and Aziridinations Using a Cheap and Readily Available Chiral Sulfide: Extensive Studies To Map Out Scope, Limitations, and Rationalization of Diastereo- and Enantioselectivities. DOI: 10.1021/ja405073w

Angew Chem Int Ed 2012, 51, 9152–9155. E I Balmond, D M Coe, M C Galan,* E M McGarrigle* — α-Selective Organocatalytic Synthesis of 2-Deoxygalactosides. DOI: 10.1002/anie.201204505

Org Lett 2011, 13, 3060–3063. E M McGarrigle,* S P Fritz, L Favereau, M Yar, V K Aggarwal* — An Efficient Synthesis of Imidazolinium salts using Vinyl Sulfonium Salts. DOI: 10.1021/ol2009472

J Am Chem Soc 2010, 132, 1828–1830.O Illa, M Arshad, A Ros, E M McGarrigle, V K Aggarwal* — ‘Practical and highly selective sulfur ylide mediated asymmetric epoxidations and aziridinations using an inexpensive, readily available chiral sulfide. Applications to the synthesis of quinine and quinidine.’ DOI: 10.1021/ja9100276 [The sulfide described is now available in either enantiomeric form from TCI, Cat no: T2578 and T2579; Aldrich 766429. The paper was highlighted by ACS Noteworthy Chemistry (March 15, 2010) and the ‘]

J Am Chem Soc 2010, 132, 7626–7630. S L Riches, C Saha, N Fontán Filgueira, E Grange, E M McGarrigle, V K Aggarwal* — ‘On the mechanism of ylide cyclopropanations: evidence for participation of intramolecular proton transfer pathways.’ DOI: 10.1021/ja910631u

Angew Chem Int Ed 2008, 47, 3784–3786. M Yar, E M McGarrigle, V K Aggarwal* — ‘An Annulation Reaction for the Synthesis of Morpholines, Thiomorpholines and Piperazines from β-Heteroatom Amino Compounds and Vinyl Sulfonium Salts.’ DOI: 10.1002/anie.200800373 [The method described has been used in patents by UCB Celltech WO2009/153554, Kudos Pharmaceuticals WO2010/136778, Genentech WO2010/014939]

J Am Chem Soc 2007, 129, 9566–9567. E Bergin, C T O’Connor, S B Robinson, E M McGarrigle, C P O’Mahony, D G Gilheany* — ‘Synthesis of P-Stereogenic Phosphorus Compounds. Asymmetric Oxidation of Phosphines under Appel Conditions.’ DOI: 10.1021/ja072925l [Winner of the 2008 Wesley Cocker award from the SCI for the best paper published in Ireland in 2007 of interest to the chemical industry]

Org Lett 2001, 3, 3435–3438. C P O’Mahony, E M McGarrigle, M F Renehan, K M Ryan, N J Kerrigan, C Bousquet, D G Gilheany* — ‘Asymmetric Alkene Epoxidation with Chromium Oxo Salen Complexes. A Systematic Study of Salen Ligand Substituents.’ DOI: 10.1021/ol010144y