Ren’s new Paper in OBC

Our latest paper has been published online in the RSC journal Org Biomol Chem. The paper describes a new way to make glycosyl chlorides using oxalyl chloride as chlorine source and just a catalytic amount of phosphine oxide. The reaction is very clean and so the product can be further reacted without purification in a subsequent organocatalytic glycosylation.

graphical abstract for website

The paper comprises work by Imlirenla, Eoghan and our UCD colleague Kirill Nikitin. This is Ren’s second paper and first as lead author, so particular congratulations to her. The research was funded by Science Foundation Ireland (mostly under a CDA grant to Eoghan). The paper can be read online (currently with a valid subscription, open access will follow, reprints available, email Eoghan):

Org Biomol Chem 2019, advance article;



Our article on Schreiner’s Catalyst is published

eEROS coverOur article on Schreiner’s catalyst has been published online in the Encyclopedia of Reagents for Organic Synthesis (e-EROS). The article reviews the applications of this thiourea-based catalyst (N,N’-[3,5-bis(trifluoromethyl)phenyl]thiourea) in organic synthesis. We previously published an article describing how this catalyst can be used in the synthesis of 2-deoxyglycosides.

The article can be read (with a subscription):

e-EROS, 2014. DOI: 10.1002/047084289X.rn01642

Research Presented in Palermo

Our preliminary findings from a collaboration with the group of Prof Peter Schreiner (Giessen) were presented in Palermo at the latest meeting of the EU COST action ORCA (CM0905). Raffael Wende prepared the poster but unfortunately fell ill and couldn’t attend the meeting, so Eoghan presented the poster in his absence. The poster described some promising initial results from Raffael and Avene. These were mostly obtained during Raffael’s visit to Dublin funded by the award of funding for a Short Term Scientific Meeting (STSM) by the COST Action to Raffael.

EU Flag hi res colour jauneCOST logo 2 blue 150dpi

New Visitor to the Group

Raffael WendeWe welcome Raffael Wende to the group! Raffael has been awarded funding by the EU-funded COST Action on organocatalysis, ORCA (CM0905), to carry out a Short Term Scientific Mission in Dublin. He is a PhD student in the group of Prof Peter Schreiner and this visit kicks off a collaboration between our two groups. Raffael will spend a month in Dublin carrying out research in the area of organocatalysis and multi-catalysis. We hope he has an enjoyable and productive visit.

We have joined the Organocatalysis COST action

Eoghan was invited to talk about our work on organocatalytic glycosylation at a meeting of the COST action ‘ORCA‘ (focusing on Organocatalysis) in Athens, Greece. There were presentations from all across the Europe (Estonia, Finland, France, Germany, Hungary, Italy, Netherlands, Portugal, Spain, Sweden, Switzerland, UK) and also a talk from Keiji Maruoka (Kyoto, Japan). Subsequently, our application to join the COST action has been accepted. We hope this will lead to further collaborations with other research groups in the EU.

ACIE article highlighted in SYNFACTS

Our recent paper in Angew. Chem. Int. Ed. has been highlighted in an article published in SYNFACTS. The article written by Prof Benjamin List and Ji Hye Kim appeared recently in SYNFACTS 2012, 8(10), 1145.

The article is also available online (to subscribers only) via