Welcome Vanessa!

We welcome Vanessa Becker to the group! Vanessa is no stranger to the lab as she did her final year BSc project with the Gilheany group last year. Her PhD studies will be in the area of organosulfur chemistry, related to projects carried out by Alex and Vinny.

New Paper in Chem Sci!

Congrats to Ren, Di and Joe on the publication in Chem Sci, the Royal Society of Chemistry’s premier journal. The paper describes a novel method for accessing difficult to make glycosidic linkages from simple starting materials. We hope it will become an enabler for scientists needing access to oligosaccharides. The work was primarily funded by and SFI-CDA grant (CDA/15/3625) which supported Ren and Di. Joe is supported by an Irish Research Council Government of Ireland Postgraduate Scholarship (GOIPG/2019/2747). We also acknowledged help from former project students Saranna and Laura, as well as the Yannick, Jin, and Jimmy, of the UCD NMR and Mass Spectrometry teams.

The article is diamond open access (funded by the RSC) and is free to read online:

Chem Sci 2021, advance article. I Pongener, D A Pepe, J J Ruddy, E M McGarrigle*— Stereoselective β-mannosylations and β-rhamnosylations from glycosyl hemiacetals mediated by lithium iodide. DOI: 10.1039/D1SC01300A

Congratulations Vinny!

Congratulations to Vinny who passed his PhD viva voce exam today! After more than 4 years of hard work the day has finally come. It’s great to have something positive to celebrate. The examination was conducted by Prof. David Procter (Uni. Manchester) as the external examiner and Assist. Prof. Marcus Baumann (UCD) as the internal examiner, with Prof. Stefan Oscarson (UCD) as chair. This was the group’s first online PhD viva. Vinny’s PhD was sponsored by a National University of Ireland Traveling PhD Studentship. As part of his PhD he worked in the lab of Prof. Varinder Aggarwal FRS at the University of Bristol. This resulted in a publication in Angew. Chem. Int. Ed. He has published a paper in Org. Lett. from some of his work in UCD and several more will follow. His next research position is a postdoctoral fellowship in the group of ERC awardee Daniele Leonori at the Univ. Manchester. Good luck with the postdoc Vinny!

New paper in J Org Chem

Congratulations to Avene on the publication of her latest paper in J Org Chem. This work was carried out in collaboration with Prof Peter Schreiner and co-workers in the Univ. of Giessen. It started out with a short-term scientific exchange funded under an EU COST action on Organocatalysis (CM0905 ORCA), when we welcomed Raffael Wende to our labs in 2014. Avene’s part was funded by an IRC government of Ireland postgraduate scholarship. The paper can be read online:

J Org Chem 2021, article asap. A Seitz, R C Wende, E Roesner, D Niedek, C Topp, A C Colgan, E M McGarrigle, and P R Schreiner* — Site-Selective Acylation of Pyranosides with Oligopeptide Catalysts. DOI: 10.1021/acs.joc.0c02772

Great Talk Alex!

Well done to Alex on her online talk at “Chemistry le Cheile – Forwarding Careers of Women in Chemistry” (online hosted by UCC). Alex’s talk was on her IRC-sponsored research, using organosulfonium salts in a new synthesis of bipyridines, which was published recently in the paper she and Vinny published in Org. Lett.

New Paper in Org. Lett.

Congrats to Vinny and Alex on the publication of their paper in Organic Letters today. A lot of hard work has gone into this so it is great to see it published. We developed a general route to 2-pyridylsulfonium salts and showed how the resulting salts could be used in the synthesis of bipyridines.

This research emanates from PhD funding for Vinny and Alex by NUI and IRC, respectively. This is Vinny’s second and Alex’s first paper, well done to both. The paper can be read online:

Org Lett, 2020, asap. V K Duong, A M Horan, E M McGarrigle – Synthesis of Pyridylsulfonium Salts and Their Application in the Formation of Functionalized Bipyridines.

DOI: 10.1021/acs.orglett.0c03048

Welcome Zoe and Colin!

We welcome Zoe and Colin Byrne to the group (they aren’t related!). They will carry out their final year BSc research projects in the group this academic year. We hope you enjoy your time in the group even though it is all a bit different this year.

Great talk Vinny!

Well done to Vinny who presented his research at the 35th Annual Postgraduate Symposium of the Heterocyclic and Synthesis Group (London (online). Vinny presented his research on applications of organosulfur chemistry to the synthesis of bipyridines.

Great Talks!

Congrats to Vinny, Alex, Dionissia and Gaffney on talks at the Dublin Chemistry PhD talks today. It was a great day of talks. Well done also to Saranna from our lab (Gilheany group side) on her talk. It was good to celebrate a positive thing.