Congrats to Alex and Vinny on their latest paper which was published online today in Org Lett. It is the second paper from Alex and Vinny in the area of organosulfur chemistry. It describes the use of heteroarylsulfonium salts to make bis-heteroaryls through reaction with heteroaryl Grignard reagents. It goes beyond our previous work making 2,4′-, 2,3′, and 2,2′-bipyridines accessible by a single method. We also described a versatile route to the biologically active natural products Caerulomycin A and E.
We are grateful to NUI, IRC and the SFI research centre SSPC for research funding. The article is available on an open access basis to free to read online:
Org Lett 2021, article asap. A M Horan, V K Duong,* E M McGarrigle*—Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts. DOI:10.1021/acs.orglett.1c03379
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