Our latest paper has been published online in the Journal of Organic Chemistry. The paper is Avene’s first paper, and details her identification of an impurity that was acting as a catalyst poison in thiourea-catalysed glycosylations. The impurity arose from the benzylation of an alcohol in DMF – a procedure that is carried out thousands of times per year all around the world. Despite this, the side-reaction that generates the impurity had not been noted in the scientific literature before. Well done to Avene on her excellent detective work, and congratulations also on her first crystal structure.
The paper can be read online at the link below:
J Org Chem 2016, Article ASAP; DOI: 10.1021/acs.joc.6b01914
If you don’t have a subscription and would like to read the article please email eoghan dot mcgarrigle at ucd dot ie to request a free article-on-request code.
The research was funded by the Irish Research Council and SFI.
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