Our latest paper was published online in Organic Lettters as an ‘as soon as possible’ article. The paper describes the use of trifluoromethyl-substituted vinylsulfonium salts for the synthesis of saturated heterocycles containing the CF3 group. The epoxide-fused heterocycles are expected to be of interest to medicinal chemists in particular. This work was carried out in collaboration with Prof Varinder Aggarwal, Sven Fritz and Tom West at the University of Bristol. We thank EPSRC and SFI for funding.
The paper can be read (with a subscription) at the following link:
Organic Letters 2012, asap; DOI: 10.1021/ol303200n
Don’t have a subscription? email Eoghan for an electronic preprint:
(eoghan_dot_mcgarrigle_at_ucd_dot_ie).
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